This was a unique workshop hosted by CIDER, The Centre for Infectious Disease Epidemiology & Research in the School of Public Health & Family Medicine, University of Cape Town, in October 2017.

The workshop's aims were to enable participants to:

1) Be able to analyse and apply the basic principles of teratology and pharmaco-epidemiology to investigate whether an exposure poses a potential risk to the mother and feotus at an individual and a population level

2) Acquire up-to-date information on various relevant teratogens

3) Acquire knowledge and skills required to design and implement teratogen surveillance systems in a resource-limited setting

4) Understand the importance and clinical application of product labelling around safety of medicines during pregnancy

5) Form part of network of African researchers, clinicians, regulators and policymakers to build capacity for protection of pregnant women and their infants

 

View presentations below and contact Dr Ushma Mehta (ushma.mehta@uct.ac.za) or Dr Emma Kalk (emma.kalk@uct.ac.za) for further information:

Introduction & principles of teratovigilance

Dr Ushma Mehta

CIDER, School of Public Health & Family Medicine, University of Cape Town, South Africa

Principles of teratology

Prof Lewis Holmes

Medical Genetics Unit, MassGeneral Hospital for Children & Dept of Paediatrics, Harvard Medical School & Director North American Antiepileptic Drug Pregnancy Registry, Boston, US

Principles of (pharmaco) epidemiology PENDING

Prof Landon Myer

CIDER, School of Public Health & Family Medicine, University of Cape Town, South Africa

Adverse birth outcomes other than birth defects: basic principles

Dr Amy Slogrove

CIDER, School of Public Health & Family Medicine, & Dept of Paediatrics & Child Health, University of Cape Town, South Africa

Beyond birth defects: the importance of other adverse birth outcomes in teratovigilance

Dr Rebecca Zash

Harvard TH Chan School of Public Health, US & Botswana Harvard AIDS Institute Partnership, Boston, US

Methods of gestational age assessment influence the observed association between ART exposure & preterm delivery: a prospective study in Cape Town

Ms Thoko Malaba

CIDER, School of Public Health & Family Medicine, University of Cape Town, South Africa

Determining the prevalence of congenital disorders in Africa: the example of South Africa 

Dr Helen Malherbe 

Genetic Alliance, South Africa

Ascertainment challenges of assembling a virtual PER based on routine data and data linkage

Prof Andrew Boulle

CIDER, School of Public Health & Family Medicine, University of Cape Town, South Africa

Resources & support: Teratology Information Services PENDING

Dr Laura Yates

Institute of Genetic Medicine, Newcastle University & UK Teratology Information Service, UK

Resources & support: The Global Health Network/Global Pharmacovigilance

Dr Elizabeth Allen

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town

Congenital infections

Dr Lavinia Schuler-Faccini 

Dept of Genetics, Federal University of Rio Grande do Sul, Brazil

The safety of ART in pregnancy

Dr Rebecca Zash

Harvard TH Chan School of Public Health, US & Botswana Harvard AIDS Institute Partnership, Boston, US

Transitioning to new ARVs: WHO 2017 Guidance PENDING

Dr Francoise Renaud

HIV/AIDS Dept, World Health Organisation

Teratogenic effects of diabetes

Dr Ed Coetzee 

Division of Maternal Fetal Medicine, Dept of Obstetrics & Gynaecology, University of Cape Town, South Africa

Fetal Alcohol Spectrum Disorder (& illicit drugs) 

Dr Mike Urban 

Division of Molecular Biology & Human Genetics, Faculty of Medicine & Health Sciences, Stellenbosch University, South Africa

Important & emerging teratogens in the developing world

Dr Lavinia Schuler-Faccini

Dept of Genetics, Federal University of Rio Grande do Sul, Brazil

Drug use during pregnancy & potential for adverse pregnancy outcome PENDING

Dr Esperanca Sevene

Faculty of Medicine, Eduardo Mondlane University & Manhica Health Research Centre, Mozambique

Barriers to obtaining an accurate medicine exposure history in pregnancy

Dr Elizabeth Allen

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town

Detecting teratogenic effects emerging after birth: challenges & tools

Dr Amy Slogrove 

CIDER, School of Public Health & Dept of Paediatrics & Child Health, University of Cape Town, South Africa

Pregnancy registries PENDING

Prof Lewis Holmes

Medical Genetics Unit, MassGeneral Hospital for Children & Dept of Paediatrics, Harvard Medical School & Director North American Antiepileptic Drug Pregnancy Registry, Boston, US

WHO Central Registry for the epidemiological surveillance of drug safety in pregnancy

Dr Christine Halleux

Special Programmes for Research & Training in Tropical Diseases, World Health Organisation

Data management in teratovigilance research: experience from the WHO Central Registry

Dr Christine Halleux

Special Programmes for Research & Training in Tropical Diseases, World Health Organisation