The World Health Organization global database for the surveillance of adverse events in the scope of active drug safety monitoring and management of anti-tuberculosis drugs (WHO Global aDSM Database) is a collaborative initiative to generate reliable evidence on the safety profile of anti-tuberculosis drugs to inform future tuberculosis treatment guidelines. It was developed and is managed by the WHO Global TB Programme (GTB) and the Special Programme for Research and Training in Tropical Diseases (TDR).

Our purpose is to facilitate pooling of safety data issued from local or national databases in the context of TB active drug safety monitoring and management (aDSM) and support early detection of any potential safety signals.

The Global aDSM Database is coordinated by a Project Management Committee comprising members from GTB and TDR at WHO. The pooled data will only be accessible to WHO, and the Project Management Committee will undertake periodic analysis of the data collected within the framework of signal detection.

Countries, surveillance projects and researchers are invited to contribute data.

WHO global database for TB active drug safety monitoring home page

aDSM Framework for Implimentation

aDSM Training Package